Rapid glycosylation of haemoglobin

A New System for Rapid Haemoglobin Estimations and Leucocyte Counts.

leucocytes in the Coulter counter. These procedures are J andglutamic performed separately and require two tubes and two eluates from diluting pipettes. The purpose of this paper is to describe a system which enables the haemoglobin estimation and leucocyte count to be made from the one diluted sample. The system dispenses with the need for pipettes and ,oncentration. diluting tubes and enables...

Rapid reprogramming of haemoglobin structure-function exposes multiple dual-antimicrobial potencies.

The intrinsic cytotoxicity of cell-free haemoglobin (Hb) has hampered the development of reliable Hb-based blood substitutes for over seven decades. Notably, recent evidence shows that the Hb deploys this cytotoxic attack against invading microbes, albeit, through an unknown mechanism. Here, we unraveled a rapid molecular reprogramming of the Hb structure-function triggered by virulent haemolyt...

False positive results with a rapid solubility test for haemoglobin S.

Rapid evaluation of N-glycosylation status of antibodies with chemiluminescent lectin-binding assay.

We constructed an assay system for the rapid detection of the glycosylation status of antibodies with a chemiluminescence-based lectin-binding assay, and investigated the glycosylation dynamics during the culture of recombinant Chinese hamster ovary cells. This rapid detection system is applicable to the high-throughput evaluation of therapeutic glycoproteins.

Persistent fetal haemoglobin and falsely high glycosylated haemoglobin levels.

Some of the routine methods of measuring glycosylated haemoglobin depend on its difference in charge from haemoglobin A and do not distinguish between glycosylated haemoglobin and fetal haemoglobin. Two insulin dependent diabetics showed persistent discrepancies between their capillary blood glucose values and their glycosylated haemoglobin values measured by agar gel electrophoresis: the blood...